and preferred sitting up dressed to lying in bed. He appeared to be going on favourably for a week, when, without warning, he was seized with a violent and prolonged convulsive fit. Death took place in about 24 hours from the first attack. On examination, a quantity of coagulated blood was found overspreading the back of both hemispheres of the brain; much serum, mixed with blood, was found effused into the pericardial and pleural cavities. The lungs were greatly congested with dark liquid blood, and the substance of the heart was pale and flabby. The peculiarity of this case was that the blood had become so thin as to exude from the heart and arteries.

The second case is that of J. G., a strong robust young man, admitted January 13th, ill a fortnight before admission. His illness was thought to have been occasioned by exposure to the sun, being employed on a farm. His symptoms indicated oppressed brain, and he died on the fifteenth day after his admission. Early and profuse perspirations marked this case, but no favourable crisis took place. On examination, unusual vascularity of the membranes of the brain was observed, also purulent softening anteriorly. The blood was fluid throughout the body.

The next fatal case was that of B. W., labourer, aged 29 years. Had been ill eight days previous to admission on March 23rd. The prominent symptom in this case was intractable vomiting. After death, on April 8th, the stomach presented a perfectly black appearance.

4th, W. K., a clerk, aged 22 years, living in the same house with the last. Admitted for mild fever on March 31st, and progressed satisfactorily for five weeks; was able to dress himself and walk up and down the ward; appetite good; was suddenly seized with violent pain in the abdomen, which speedily swelled, and became exquisitely tender. Death took place in thirty hours from the first attack of pain, and on inspection a small round hole was discovered in the small intestines, occasioned by a perforating ulcer, and permitting feculent matter to escape. It is remarkable that in this case there was no diarrhoea.

5th, F. T., tutor, aged 23 years. After ten days’ illness, was admitted on May 3rd, labouring under mild fever, attended by gentle perspirations. At the end of three weeks, when he was believed to be convalescent, he was suddenly seized with a fit of convulsions. These soon ceased, but were followed by maniacal symptoms and most profuse perspiration, which alternated with diarrhoea, and produced the utmost prostration. Death took place in 43 days from admission. The brain was found full of serum, and the left lung was infiltrated with purulent matter.

6th. At a late period of the year, viz., September 30th, W.P., a seaman, was admitted in the last stage of typhoid fever. Died on the third day from admission. Numerous patches of ulceration were found in the small intestines. The blood was fluid and dark.

Abscesses and Ulcers.

There were two fatal cases under this head.

1st. J.J., labourer, aged 61 years, admitted October 25th, 1862, for ulcers on the legs and general debility. After the ulcers healed, he became affected with chronic vomiting and entire loss of appetite. Death took place about 4 months after admission. There was no inspection of the body.

2nd. W.T., a farmer, aged 35 years, admitted on June 16th, with an enormous abscess of right thigh, apparently the consequence of fever, from which he was convalescent on admission. His strength gradually sank under the profuse suppuration, and death took place 16 days after admission.

Brain, &c.

W.E., discharged soldier, aged 45 years, admitted June 1st, 1857, having been thrown from horseback on his head. He never fully recovered from the effect of this injury, always complaining of giddiness, headache, &c. He died on March 4th, and on examination the back part of the skull was found to be of enormous thickness, amounting in parts to 1½ inch. The state of the brain and its membranes was healthy.

2nd. J.H., ex-policeman, aged 30 years, admitted September 3, 1862, for idiocy, dependent on diseased brain. The approach of this disease was very gradual, but when fully developed its progress was rapid. Death took place nine months after admission. Much serum was found in and upon the brain, the substance of which was firm.

3rd. M.C., a Frenchman, aged 55 years, was admitted in a state approaching to insensibility on August 22nd, and died three days thereafter. Great effusion of serum was found in and on the brain, with opacity and thickening of the arachnoid membrane. There existed in this case an impermeable stricture.

Lungs and Pleura.

The first case under this head was a very remarkable one. D.B., a tanner, aged 50 years, admitted September 7th, with cough and difficulty of breathing, and utter prostration. Death took place three days after admission. On examination, four pints of blood, fluid and coagulated, were found filling the right pleura, and by its pressure completely condensing the lung. In the lower lobe of this lung, an ulcerated opening, large enough to admit the point of a finger, was discovered. The left lung was perfectly healthy; the heart was enlarged. The liver presented the ‘nutmeg’ character. It is remarkable that there was no expectoration of blood in this case. The patient stated that in a fit of coughing, he felt something give way in his side, and was immediately seized with difficulty of breathing. Nothing was observed in this case to lead to the conclusion that disease had originated otherwise than by accident.

2nd. W.M., farm-servant, aged 53 years, admitted January 24th, with pneumonia, and subsequently became dropsical. Gradually declined, and died on September 20. The lungs were found condensed, and both sides of the chest contained much serum. Heart enlarged; liver “nutmeg;” kidneys shrunken and granular.